Hemophilia: A Review of Perioperative Management for Cardiac Surgery

Authors: Kwak, J; Mazzeffi, M; Boggio, LN; Simpson, ML; Tanaka, KA

Affiliations: Loyola Univ, Dept Anesthesiol & Perioperat Med, Med Ctr, 2160 South First Ave, Maywood, IL 60153 USA; Univ Maryland, Dept Anesthesiol, Sch Med, Baltimore, MD 21201 USA; Rush Univ, Rush Hemophilia & Thrombophilia Ctr, Dept Med, Chicago, IL 60612 USA; Rush Univ, Dept Pediat, Rush Hemophilia & Thrombophilia Ctr, Chicago, IL 60612 USA.

Publication: Journal of Cardiothoracic and Vascular Anesthesia ; 2022 ; 36. 246–257

Abstract: Hemophilia is an X-linked, recessive bleeding disorder. Improvements in factor replacement therapy and overall approach to hemophilia management have increased the lifespan and quality of life for patients with hemophilia. Thus, they are presenting for cardiac surgery related to agerelated atherosclerosis, vascular disorders, and degenerative valvular disease. Although challenging, cardiac surgery can be performed safely with appropriate planning, using a multidisciplinary approach. This article provides a narrative review and framework for the perioperative management of patients with hemophilia A and B undergoing cardiac surgery.