COVID-19 and the Heart

Authors: Akhmerov, A. and Marban, E.

Publication: Circ.Res; April 2020

Affiliations: Smidt Heart Institute, Cedars-Sinai Medical Center, UNITED STATES; Heart Institute, Cedars-Sinai Medical Center, UNITED STATES.

Abstract: Infection with the novel coronavirus, SARS-CoV-2, produces a clinical syndrome known as COVID-19. When severe, COVID-19 is a systemic illness characterized by hyperinflammation, cytokine storm and elevations of cardiac injury biomarkers. Here we review what is known about the pathophysiology of COVID-19, its cardiovascular manifestations, and emerging therapeutic prospects. In this rapidly moving field, this review was comprehensive as of April 3, 2020.